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Virulence factors in vancomycin-resistant and vancomycin- susceptible Enterococcus faecalis from Brazil.


ABSTRACT: Enterococci are members of commensal flora of animals and insects, but are also important opportunistic pathogens. Our objective was to observe if there was any difference of virulence in several groups of E. faecalis, mainly between vancomycin-resistant E. faecalis (VREFS) of colonization and infection. VREFS and vancomycin-sensitive E. faecalis from Brazil were screened for the presence of virulence factor genes. Phenotypic assays were used to assess in vitro expression, to understand the pathogenic potential of these isolates and to determine whether a correlation exists between virulence and antibiotic resistance. Different virulence profiles were found suggesting that the disseminating clone may have generated several variations. However, our study showed that one constellation of tra

SUBMITTER: Camargo IL 

PROVIDER: S-EPMC3768389 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature