Association of TLR4 polymorphisms with subclinical mastitis in Brazilian holsteins.

ABSTRACT: The identification of dairy cows with greater or lower potential to develop mastits has been pursued for many years among different segments of the milk industry, including governmental organizations. Genomic studies have suggested that Single Nucleotide Polymorphisms (SNPs) within the pattern recognition receptors (PRR) could lead to different responses to pathogens, and consequently result in mastitis resistance or susceptibility. To investigate whether toll like receptor 4 (TLR4) gene is associated with subclinical mastitis in Holstein cows from a property in the state of Goiás, Brazil, TaqMan allelic discrimination and somatic cell count were performed. One hundred and fifty milk samples were analyzed for SCC and centesimal composition. Twenty percent of those samples with SCC above 20

SUBMITTER: de Mesquita AQ 

PROVIDER: S-EPMC3768839 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature