Fusarium keratitis in Brazil: genotyping, in vitro susceptibilities, and clinical outcomes.

ABSTRACT:

Background

The purpose of this paper is to describe clinical characteristics and determine correlations between clinical outcomes and antifungal susceptibility among molecularly characterized ocular Fusarium isolates in Brazil.

Methods

Forty-one Fusarium isolates obtained from 41 eyes of 41 patients were retrieved from the ophthalmic microbiology laboratory at São Paulo Federal University and grown in pure culture. These isolates were genotyped and antifungal susceptibilities determined for each isolate using a broth microdilution method. The corresponding medical records were reviewed to determine clinical outcomes.

Results

The 41 isolates were genotypically classified as Fusarium solani species complex (36 isolates, 88%), Fusarium oxysporum species complex (two isol

SUBMITTER: Oechsler RA 

PROVIDER: S-EPMC3769409 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature