Stressful events, social support, and cognitive function in middle-aged adults with a family history of Alzheimer's disease.

ABSTRACT:

Objective

To examine the associations of stressful experiences and social support with cognitive function in a sample of middle-aged adults with a family history of Alzheimer's disease (AD).

Method

Using data from the Wisconsin Registry for Alzheimer's Prevention (WRAP; N = 623), we evaluated relationships between stressful events experienced in the past year, as well as social support, and cognitive performance in four domains: speed and flexibility, immediate memory, verbal learning and memory, and working memory. We assessed interactions between psychosocial predictors, and with APOE ε4 status.

Results

Greater number of stressful events was associated with poorer performance on tests of speed and flexibility. Greater social support was associated with better perfor

SUBMITTER: Zuelsdorff ML 

PROVIDER: S-EPMC3769466 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature