Catechins in dietary supplements and hepatotoxicity.

ABSTRACT:

Background

Many herbal dietary supplements (HDS) contain green tea extract (GTE) and its component catechins, although their presence may not always be indicated on the product label.

Purpose

Because GTE and catechins have been implicated in human hepatotoxicity in several case reports, our objective was to determine whether catechins were present in HDS that were implicated in hepatotoxicity, even if not identified among the labeled ingredients, and whether these compounds could be associated with liver injury.

Methods

We assayed 97 HDS implicated in human hepatotoxicity for catechins.

Results

We found that 29 of 73 HDS (39.7%) that did not identify GTE or any of its component catechins on their label contained catechins. Among patients with confirmed hepatoto

SUBMITTER: Navarro VJ 

PROVIDER: S-EPMC3769469 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature