Dissecting virus-plant interactions through proteomics approaches.

ABSTRACT: Plant viruses exploit cellular factors, including host proteins, membranes and metabolites, for their replication in infected cells and to establish systemic infections. Besides traditional genetic, molecular, cellular and biochemical methods studying plant-virus interactions, both global and specialized proteomics methods are emerging as useful approaches for the identification of all the host proteins that play roles in virus infections. The various proteomics approaches include measuring differential protein expression in virus infected versus noninfected cells, analysis of viral and host protein components in the viral replicase or other virus-induced complexes, as well as proteome-wide screens to identify host protein - viral protein interactions using protein arrays or yeast two-hybr

SUBMITTER: Xu K 

PROVIDER: S-EPMC3769790 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature