Pretreatment EEG in childhood absence epilepsy: associations with attention and treatment outcome.

ABSTRACT:

Objective

In children with newly diagnosed childhood absence epilepsy (CAE), determine pretreatment EEG features and their associations with baseline neuropsychological function and short-term treatment outcome.

Methods

In a multicenter, randomized clinical trial, patients with CAE underwent a pretreatment, 1-hour video-EEG and neuropsychological testing with freedom-from-failure and seizure-freedom (SF) outcome assessed at the 16- to 20-week visit.

Results

Detailed evaluation of the pretreatment EEG was possible for 99.8% of participants (445/446). Median time to first seizure was 6.0 minutes (range 0-59 minutes), median number of seizures was 5 (range 1-60), and median seizure duration was 10.8 seconds (range 3.3-77.6 seconds). Median duration of shortest seizure pe

SUBMITTER: Dlugos D 

PROVIDER: S-EPMC3770172 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature