Maternal smoking, alcohol, and coffee use during pregnancy and son's risk of testicular cancer.

ABSTRACT: It has been suggested that increased risk for testicular cancer occurring worldwide may be due to exposures during fetal development. Lifestyle or environmental exposures may be the most important predictors of risk. However, few studies have directly examined these exposures prospectively. The Child Health and Development Studies is a 40-year follow-up of 20,530 pregnancies occurring between 1959 and 1967. There were 20 cases of testicular cancer diagnosed through 2003 among sons with a maternal interview in early pregnancy. Cases were matched to three controls on birth year and race. Odds ratios and 95% confidence intervals were calculated with exact conditional logistic regression. Compared to controls, mothers of testicular cancer cases were more likely to drink alcohol (unadjusted odd

SUBMITTER: Mongraw-Chaffin ML 

PROVIDER: S-EPMC3770444 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature