Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial.

ABSTRACT:

Background & aims

Although percutaneous liver biopsy is a standard diagnostic procedure, it has drawbacks, including risk of serious complications. It is not known whether persons with advanced chronic liver disease have a greater risk of complications from liver biopsy than patients with more mild, chronic liver disease. The safety and complications of liver biopsy were examined in patients with hepatitis C-related bridging fibrosis or cirrhosis who were enrolled in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial.

Methods

Standard case report forms from 2740 liver biopsies performed at 10 study sites between 2000 and 2006 were reviewed for serious adverse events, together with information from questionnaires completed by investigators about details of

SUBMITTER: Seeff LB 

PROVIDER: S-EPMC3771318 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature