Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis.

ABSTRACT:

Objective

To provide a comprehensive overview of the risk of venous thrombosis in women using different combined oral contraceptives.

Design

Systematic review and network meta-analysis.

Data sources

PubMed, Embase, Web of Science, Cochrane, Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier, and ScienceDirect up to 22 April 2013.

Review methods

Observational studies that assessed the effect of combined oral contraceptives on venous thrombosis in healthy women. The primary outcome of interest was a fatal or non-fatal first event of venous thrombosis with the main focus on deep venous thrombosis or pulmonary embolism. Publications with at least 10 events in total were eligible. The network meta-analysis was performed using an extens

SUBMITTER: Stegeman BH 

PROVIDER: S-EPMC3771677 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature