Sex differences in arterial stiffness and ventricular-arterial interactions.

ABSTRACT:

Objectives

This study sought to assess sex differences in ventricular-arterial interactions.

Background

Heart failure with preserved ejection fraction is more prevalent in women than in men, but the basis for this difference remains unclear.

Methods

Echocardiography and arterial tonometry were performed to quantify arterial and ventricular stiffening and interaction in 461 participants without heart failure (189 men, age 67 ± 9 years; 272 women, age 65 ± 10 years). Aortic characteristic impedance (Z(c)), total arterial compliance (pulsatile load), and systemic vascular resistance index (steady load) were compared between men and women, and sex-specific multivariable regression analyses were performed to assess associations of these arterial parameters with diastolic d

SUBMITTER: Coutinho T 

PROVIDER: S-EPMC3773521 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature