Colorectal cancer survival in the USA and Europe: a CONCORD high-resolution study.

ABSTRACT:

Objectives

To assess the extent to which stage at diagnosis and adherence to treatment guidelines may explain the persistent differences in colorectal cancer survival between the USA and Europe.

Design

A high-resolution study using detailed clinical data on Dukes' stage, diagnostic procedures, treatment and follow-up, collected directly from medical records by trained abstractors under a single protocol, with standardised quality control and central statistical analysis.

Setting and participants

21 population-based registries in seven US states and nine European countries provided data for random samples comprising 12 523 adults (15-99 years) diagnosed with colorectal cancer during 1996-1998.

Outcome measures

Logistic regression models were used to compare adhe

SUBMITTER: Allemani C 

PROVIDER: S-EPMC3773629 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature