Third ventricular enlargement in early stages of multiple sclerosis is a predictor of motor and neuropsychological deficits: a cross-sectional study.

ABSTRACT:

Objectives

Whether transcranal sonography (TCS) depicted third ventricular enlargement as a sign of brain atrophy is predictive for neuropsychological deficits in mildly affected patients with multiple sclerosis (MS).

Design

Cross-sectional study of a cohort of mildly diseased patients with MS.

Setting

Neurological MS outpatient clinic at a large teaching hospital in central Europe.

Participants

Fifty-four patients with MS (16 men, 38 women, mean age 40±10 years, mean disease duration 6±5 years; mean Expanded Disability Status Scale 2±1.3) and 33 healthy controls (12 men, 21 women; 38±11 years) underwent clinical examination, an assessment of the third ventricle width by means of TCS and the Brief Repeatable Battery of Neuropsychological tests for MS, the 25-Fe

SUBMITTER: Muller M 

PROVIDER: S-EPMC3773637 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature