Respiratory dysrhythmia in dementia with Lewy bodies: a cross-sectional study.

ABSTRACT:

Objectives

Dementia with Lewy bodies (DLB) is the second most common form of neurodegenerative dementia after Alzheimer's disease (AD). DLB is characterised by intracytoplasmic inclusions called Lewy bodies that are often seen in the brainstem. Because modulation of the respiratory rhythm is one of the most important functions of the brainstem, patients with DLB may exhibit dysrhythmic breathing. This hypothesis has not yet been systematically studied. Therefore, we evaluated the association between DLB and dysrhythmic breathing.

Design

In this cross-sectional study consecutive inpatients who were admitted for the evaluation of progressive cognitive impairment were enrolled. We assessed breathing irregularity using polysomnographic recordings on bed rest with closed eyes, wi

SUBMITTER: Hibi S 

PROVIDER: S-EPMC3773650 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature