Long-term benefit of hepatitis C therapy in a safety net hospital system: a cross-sectional study with median 5-year follow-up.

ABSTRACT:

Objectives

To demonstrate the survival benefit from sustained virological response (SVR) in a safety net hospital population with limited resources for hepatitis C virus (HCV) therapy.

Design and setting

We conducted a retrospective study at an urban safety net hospital in the USA.

Participants and intervention

242 patients receiving standard HCV therapy between 2001 and 2006.

Primary and secondary outcome measures

Response rates, including SVR, were recorded for each patient. Univariate and multivariate analyses were performed to identify predictors of SVR and 5-year survival.

Results

A total of 242 eligible patients were treated. Treatment was completed in 197 (81%) patients, with 43 patients discontinuing therapy early-32 due to adverse events and 11

SUBMITTER: Singal AG 

PROVIDER: S-EPMC3773652 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature