Ontology highlight
ABSTRACT:
SUBMITTER: Illig T
PROVIDER: S-EPMC3773904 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Nature genetics 20091227 2
Serum metabolite concentrations provide a direct readout of biological processes in the human body, and they are associated with disorders such as cardiovascular and metabolic diseases. We present a genome-wide association study (GWAS) of 163 metabolic traits measured in human blood from 1,809 participants from the KORA population, with replication in 422 participants of the TwinsUK cohort. For eight out of nine replicated loci (FADS1, ELOVL2, ACADS, ACADM, ACADL, SPTLC3, ETFDH and SLC16A9), the ...[more]