Elevated reward region responsivity predicts future substance use onset but not overweight/obesity onset.

ABSTRACT:

Background

We tested the hypotheses that adolescents who show elevated reward region responsivity are at increased risk for initial onset of overweight/obesity and substance use, which is important because there have been no such prospective tests of the reward surfeit model of these motivated behaviors.

Methods

One hundred sixty-two adolescents (mean age = 15.3±1.06 years) with healthy weights (mean body mass index = 20.8±1.90) completed functional magnetic resonance imaging paradigms that assessed neural activation in response to receipt and anticipated receipt of palatable food and monetary reward; body fat and substance use were assessed at baseline and 1-year follow-up.

Results

Elevated caudate (r = .31, p<.001) and putamen (r = .28, p<.001) response to monetary

SUBMITTER: Stice E 

PROVIDER: S-EPMC3774523 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature