Comorbidities are associated with poorer outcomes in community patients with rheumatoid arthritis.

ABSTRACT:

Objective

To evaluate the impact of comorbidities on achieving remission by examining changes in the clinical disease activity index (CDAI) in RA patients in the community-based Consortium of Rheumatology Researchers of North America (CORRONA) registry.

Methods

A subcohort of 1548 RA subjects with varying disease duration met the following inclusion criteria: started a DMARD/biologic agent, continued therapy ≥ 3 months, CDAI ≥ 2.8 at study entry and followed longitudinally from baseline to follow-up (mean time 7.46 months). Patients reported comorbidities according to a standardized list of 33 conditions. Entry characteristics were compared across age categories using one-way analysis of variance. Linear and logistic regression models were constructed to assess characteristi

SUBMITTER: Ranganath VK 

PROVIDER: S-EPMC3775293 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature