Task vs. rest-different network configurations between the coactivation and the resting-state brain networks.

ABSTRACT: There is a growing interest in studies of human brain networks using resting-state functional magnetic resonance imaging (fMRI). However, it is unclear whether and how brain networks measured during the resting-state exhibit comparable properties to brain networks during task performance. In the present study, we investigated meta-analytic coactivation patterns among brain regions based upon published neuroimaging studies, and compared the coactivation network configurations with those in the resting-state network. The strength of resting-state functional connectivity between two regions were strongly correlated with the coactivation strength. However, the coactivation network showed greater global efficiency, smaller mean clustering coefficient, and lower modularity compared with the rest

SUBMITTER: Di X 

PROVIDER: S-EPMC3775427 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature