High prevalence of vitamin D deficiency in patients with basal cell nevus syndrome.

ABSTRACT:

Objectives

To evaluate vitamin D status in patients with basal cell nevus syndrome (BCNS) who practice photoprotection because of their genetic predisposition to skin cancer and to determine risk factors for deficiency.

Design

Retrospective cohort study.

Setting

Academic medical centers.

Patients

Forty-one ambulatory patients with BCNS who participated in a 2-year chemoprevention clinical trial. Population-based controls (n = 360) were selected and matched by age, sex, Fitzpatrick skin type, and season/geography.

Main outcome measures

Levels of 25-hydroxyvitamin D (25[OH]D) and vitamin D deficiency (defined as a 25[OH]D level of ≤20 ng/mL).

Results

Twenty-three patients with BCNS (56%) were vitamin D deficient. Patients with BCNS had mean 25(OH)D

SUBMITTER: Tang JY 

PROVIDER: S-EPMC3775573 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature