Postoperative hyperphosphatemia significantly associates with adverse survival in colorectal cancer patients.

ABSTRACT:

Background and aim

Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored. Given new insights into the importance of hyperphosphatemia in CRC, we sought to evaluate the association of hyperphosphatemia with the clinical outcomes of this disease.

Methods

In a retrospective analysis of a well-characterized clinic-based cohort with 1241 CRC patients, we assessed the association of postoperative hyperphosphatemia with patient overall survival.

Results

Postoperative hyperphosphatemia measured within the first month after surgery was significantly associated with CRC survival. Compared to patients with a normal phosphate level,

SUBMITTER: Ye Z 

PROVIDER: S-EPMC3775915 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature