Dietary flavonoid intake and smoking-related cancer risk: a meta-analysis.

ABSTRACT:

Purpose

To systematically investigate the effects of dietary flavonoids and flavonoid subclasses on the risk of smoking-related cancer in observational studies.

Methods

Summary estimates and corresponding standard errors were calculated using the multivariate-adjusted odds ratio (OR) or relative risk (RR) and 95% CI of selected studies and weighted by the inverse variance.

Results

A total of 35 studies, including 19 case-controls (9,525 cases and 15,835 controls) and 15 cohort studies (988,082 subjects and 8,161 cases), were retrieved for the meta-analysis. Total dietary flavonoids and most of the flavonoid subclasses were inversely associated with smoking-related cancer risk (OR: 0.82, 95% CI: 0.72-0.93). In subgroup analyses by cancer site, significant associations

SUBMITTER: Woo HD 

PROVIDER: S-EPMC3777962 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature