Ontology highlight
ABSTRACT:
SUBMITTER: Souquet B
PROVIDER: S-EPMC3778009 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Souquet Benoit B Abby Emilie E Hervé Roxane R Finsterbusch Friederike F Tourpin Sophie S Le Bouffant Ronan R Duquenne Clotilde C Messiaen Sébastien S Martini Emmanuelle E Bernardino-Sgherri Jacqueline J Toth Attila A Habert René R Livera Gabriel G
PLoS genetics 20130919 9
Meiotic recombination is a mandatory process for sexual reproduction. We identified a protein specifically implicated in meiotic homologous recombination that we named: meiosis specific with OB domain (MEIOB). This protein is conserved among metazoan species and contains single-strand DNA binding sites similar to those of RPA1. Our studies in vitro revealed that both recombinant and endogenous MEIOB can be retained on single-strand DNA. Those in vivo demonstrated the specific expression of Meiob ...[more]