Vitamin D intake and lung cancer risk in the Women's Health Initiative.

ABSTRACT:

Background

Prior research suggests that vitamin D protects against lung cancer only among certain subgroups.

Objectives

We investigated whether vitamin D intake was associated with lung cancer and explored whether vitamin A intake modified the association.

Design

Prospective cohort data from 128,779 postmenopausal women, including 1771 incident lung cancers in the Women's Health Initiative (Clinical Trials and Observational Study) 1993-2010, were analyzed. Twelve percent of women received active intervention (1 g Ca + 400 IU vitamin D3/d) in the Calcium/Vitamin D Trial. Baseline total intake included both dietary intake (from food-frequency questionnaires) and supplement intake (from bottle labels). HRs were estimated by Cox proportional hazard models.

Results

SUBMITTER: Cheng TY 

PROVIDER: S-EPMC3778856 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature