High-incidence of human adenoviral co-infections in taiwan.

ABSTRACT:

Background

Respiratory infections caused by adenovirus (HAdV) are common year round. Recently, a significant increase of adenoviral infections was observed in Taiwan.

Objective

To understand the prevalence and molecular epidemiology of respiratory adenovirus circulating in Taiwan for the past decade.

Study design

One hundred and twenty-six human adenoviruses, isolated between 2002 to 2011, were characterized via DNA sequencing of the hexon and fiber genes. The nucleotide sequences were then compared by phylogenetic analysis.

Results

HAdV-B3 accounted for 64.3% (81/126) and peaked almost every year, whereas the sequences of hexon and fiber genes of HAdV-B3 were highly conserved in different years. A high incidence of co-infection of adenoviruses was observed (19

SUBMITTER: Wang SL 

PROVIDER: S-EPMC3779158 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature