Genetic characterization of the hemagglutinin genes of wild-type measles virus circulating in china, 1993-2009.

ABSTRACT:

Background

China experienced several large measles outbreaks in the past two decades, and a series of enhanced control measures were implemented to achieve the goal of measles elimination. Molecular epidemiologic surveillance of wild-type measles viruses (MeV) provides valuable information about the viral transmission patterns. Since 1993, virologic surveillnace has confirmed that a single endemic genotype H1 viruses have been predominantly circulating in China. A component of molecular surveillance is to monitor the genetic characteristics of the hemagglutinin (H) gene of MeV, the major target for virus neutralizing antibodies.

Principal findings

Analysis of the sequences of the complete H gene from 56 representative wild-type MeV strains circulating in China during 1993-20

SUBMITTER: Xu S 

PROVIDER: S-EPMC3779233 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature