Socioeconomic status and lung cancer: unraveling the contribution of genetic admixture.

ABSTRACT:

Objectives

We examined the relationship between genetic ancestry, socioeconomic status (SES), and lung cancer among African Americans and Latinos.

Methods

We evaluated SES and genetic ancestry in a Northern California lung cancer case-control study (1998-2003) of African Americans and Latinos. Lung cancer case and control participants were frequency matched on age, gender, and race/ethnicity. We assessed case-control differences in individual admixture proportions using the 2-sample t test and analysis of covariance. Logistic regression models examined associations among genetic ancestry, socioeconomic characteristics, and lung cancer.

Results

Decreased Amerindian ancestry was associated with higher education among Latino control participants and greater African ances

SUBMITTER: Aldrich MC 

PROVIDER: S-EPMC3780736 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature