Cost-effectiveness of surveillance strategies after treatment for high-grade anal dysplasia in high-risk patients.

ABSTRACT:

Background

Anal cancer is one of the most common cancers affecting human immunodeficiency virus (HIV)-infected male patients. Currently, there is no consensus on posttreatment surveillance of HIV-infected men who have sex with men (MSM) who have been treated for high-grade intraepithelial neoplasia (HGAIN), the likely precursor to anal cancer.

Objective

The aim of this study was to assess the cost-effectiveness of a range of strategies for anal cancer surveillance in HIV-infected MSM previously treated for HGAIN.

Methods

We developed a Markov model to project quality-adjusted life expectancy, lifetime costs, and the incremental cost-effectiveness ratios of 5 strategies using high-resolution anoscopy (HRA) and/or anal cytology testing after treatment.

Results

Pe

SUBMITTER: Assoumou SA 

PROVIDER: S-EPMC3780795 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature