Ontology highlight
ABSTRACT:
SUBMITTER: Jaureguiberry G
PROVIDER: S-EPMC3782194 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Nephron. Physiology 20120101 1-2
<h4>Background/aims</h4>Calcium homeostasis requires regulated cellular and interstitial systems interacting to modulate the activity and movement of this ion. Disruption of these systems in the kidney results in nephrocalcinosis and nephrolithiasis, important medical problems whose pathogenesis is incompletely understood.<h4>Methods</h4>We investigated 25 patients from 16 families with unexplained nephrocalcinosis and characteristic dental defects (amelogenesis imperfecta, gingival hyperplasia, ...[more]