Development and application of stable phantoms for the evaluation of photoacoustic imaging instruments.

ABSTRACT: Photoacoustic imaging combines the high contrast of optical imaging with the spatial resolution and penetration depth of ultrasound. This technique holds tremendous potential for imaging in small animals and importantly, is clinically translatable. At present, there is no accepted standard physical phantom that can be used to provide routine quality control and performance evaluation of photoacoustic imaging instruments. With the growing popularity of the technique and the advent of several commercial small animal imaging systems, it is important to develop a strategy for assessment of such instruments. Here, we developed a protocol for fabrication of physical phantoms for photoacoustic imaging from polyvinyl chloride plastisol (PVCP). Using this material, we designed and constructed a ran

SUBMITTER: Bohndiek SE 

PROVIDER: S-EPMC3783368 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature