Phentermine and topiramate extended-release: a new treatment for obesity and its role in a complications-centric approach to obesity medical management.

ABSTRACT:

Introduction

Weight-management options include lifestyle modifications, bariatric surgery and, until recently, limited pharmacotherapy. Phentermine and topiramate extended-release (phentermine/topiramate ER) has recently been approved in the USA for chronic weight management in obese adults and overweight adults with weight-related co-morbidities in conjunction with a reduced-calorie diet and increased physical activity.

Areas covered

This review describes the pharmacology and clinical trials data for phentermine/topiramate ER and its role in a complications-centric approach to medical care of the overweight and obese patient.

Expert opinion

Phentermine/topiramate ER is an effective and safe weight-loss medication that can produce and sustain approximately 10% loss of

SUBMITTER: Garvey WT 

PROVIDER: S-EPMC3786546 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature