Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures.

ABSTRACT: A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand-receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of cancer cells. Subsequently, these captured cells are released upon a physical stimulation with outstanding cell viability.

SUBMITTER: Hou S 

PROVIDER: S-EPMC3786692 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature