Depression and blood pressure in high-risk children and adolescents: an investigation using two longitudinal cohorts.

ABSTRACT:

Objective

To examine the relationship between blood pressure and depressive disorder in children and adolescents at high risk for depression.

Design

Multisample longitudinal design including a prospective longitudinal three-wave high-risk study of offspring of parents with recurrent depression and an on-going birth cohort for replication.

Setting

Community-based studies.

Participants

High-risk sample includes 281 families where children were aged 9-17 years at baseline and 10-19 years at the final data point. Replication cohort includes 4830 families where children were aged 11-14 years at baseline and 14-17 years at follow-up and a high-risk subsample of 612 offspring with mothers that had reported recurrent depression.

Main outcome measures

The new-ons

SUBMITTER: Hammerton G 

PROVIDER: S-EPMC3787406 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature