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Lipids and lipoprotein ratios: contribution to carotid intima media thickness in adolescents and young adults with type 2 diabetes mellitus.


ABSTRACT:

Background

Dyslipidemia is common among adolescents with type 2 diabetes (T2D).

Objective

To assess whether the lipoprotein ratios of low-density lipoprotein (LDL) cholesterol/high-density lipoprotein (HDL) cholesterol or triglycerides/HDL or non-HDL cholesterol are more useful than the traditional lipid panel to predict increased arterial thickness in adolescents and young adults with T2D.

Methods

We evaluated 244 adolescents and young adults with T2D in a cross-sectional study (mean age 18 years; 56% African American; 65% female). Demographics, anthropometrics, and laboratory data were collected. Arterial thickness was assessed with carotid intima media thickness (IMT). Bivariate correlations and general linear models were used to determine the independent contribut

SUBMITTER: Shah AS 

PROVIDER: S-EPMC3788355 | biostudies-literature | 2013 Sep-Oct

REPOSITORIES: biostudies-literature