Cardiorenal syndrome: ultrafiltration therapy for heart failure--trials and tribulations.

ABSTRACT: Heart failure remains the leading cause of hospitalization in older patients and is considered a growing public health problem with a significant financial burden on the health care system. The suboptimal efficacy and safety profile of diuretic-based therapeutic regimens coupled with unsatisfactory results of the studies on novel pharmacologic agents have positioned ultrafiltration on the forefront as an appealing therapeutic option for patients with acute decompensated heart failure (ADHF). In recent years, substantial interest in the use of ultrafiltration has been generated due to the advent of dedicated portable devices and promising results of trials focusing both on mechanistic and clinical aspects of this therapeutic modality. This article briefly reviews the proposed benefits of ul

SUBMITTER: Kazory A 

PROVIDER: S-EPMC3789341 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature