Single FGF-23 measurement and time-averaged plasma phosphate levels in hemodialysis patients.

ABSTRACT:

Background and objectives

Plasma phosphate levels display considerable intraindividual variability. The phosphatonin fibroblast growth factor 23 is a central regulator of plasma phosphate levels, and it has been postulated to be a more stable marker than conventional CKD-mineral and bone disorder parameters. Thus, fibroblast growth factor 23 has been hypothesized to reflect time-averaged plasma phosphate levels in CKD patients.

Design, setting, participants, & measurements

Among 40 patients from the outpatient dialysis center, serial measurements of plasma calcium and phosphate (before every dialysis session) as well as C-terminal fibroblast growth factor 23, parathyroid hormone, and alkaline phosphatase (one time weekly) were performed over a study period of 4 weeks in Nove

SUBMITTER: Seiler S 

PROVIDER: S-EPMC3789357 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature