Curing HIV: lessons from cancer therapy.

ABSTRACT:

Purpose of review

Interest in finding a potential 'cure' for HIV has taken on greater interest and urgency since the report of an individual who underwent allogeneic stem cell transplant from a CCR5 delta 32 homozygote donor after high-dose chemotherapy for acute myeloid leukemia. The potential role of cancer chemotherapy and other cancer-directed treatment approaches is discussed in the context of their potential role in helping to eliminate HIV from the infected host.

Recent findings

Cancer chemotherapy and other cancer-targeted agents have been used successfully in treating a variety of malignancies in both HIV-infected and HIV-uninfected individuals. Lessons learned from these strategies may be of importance in helping to define more effective ways of controlling and eli

SUBMITTER: Mitsuyasu R 

PROVIDER: S-EPMC3789644 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature