Significantly increased risk of cardiovascular disease among patients with gallstone disease: a population-based cohort study.

ABSTRACT:

Objective

To investigate whether gallstone disease (GD) increases the risk of developing cardiovascular disease (CVD) in a large population-based cohort.

Methods

A study population including 6,981 patients with GD was identified from The Taiwan National Health Insurance Research Database between 2004 and 2005. GD patients were defined as patients with principal discharge diagnoses of cholelithiasis using the ICD-9-CM code 574. 27,924 patients without GD were randomly selected and matched for age and gender. All patients were followed for 6 years or until diagnosis for CVD. Cox proportional hazards regression model was used to assess the risk of developing CVD with adjustment for age, gender and co-morbid conditions.

Results

During the six years follow-up period, 935 p

SUBMITTER: Olaiya MT 

PROVIDER: S-EPMC3789705 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature