Chimeric protein complexes in hybrid species generate novel phenotypes.

ABSTRACT: Hybridization between species is an important mechanism for the origin of novel lineages and adaptation to new environments. Increased allelic variation and modification of the transcriptional network are the two recognized forces currently deemed to be responsible for the phenotypic properties seen in hybrids. However, since the majority of the biological functions in a cell are carried out by protein complexes, inter-specific protein assemblies therefore represent another important source of natural variation upon which evolutionary forces can act. Here we studied the composition of six protein complexes in two different Saccharomyces "sensu stricto" hybrids, to understand whether chimeric interactions can be freely formed in the cell in spite of species-specific co-evolutionary forces,

SUBMITTER: Piatkowska EM 

PROVIDER: S-EPMC3789821 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature