Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature.

ABSTRACT: The effects of salt concentration and temperature on the thermodynamics of DNA minor groove binding have quite different signatures: binding enthalpy is salt concentration independent but temperature dependent. Conversely, binding free energy is salt dependent but essentially temperature independent through enthalpy-entropy compensation.

SUBMITTER: Wang S 

PROVIDER: S-EPMC3791883 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature