Reproducibility of interictal EEG-fMRI results in patients with epilepsy.

ABSTRACT:

Purpose

Combined electroencephalography (EEG) and functional MRI (EEG-fMRI) can be useful in the evaluation of epilepsy patients. The reproducibility of EEG-fMRI findings needs to be established to consider it as a clinically valuable method. We addressed the intrasubject reproducibility of EEG-fMRI and the possible superiority of higher magnetic field strength in patients who were scanned twice.

Methods

Fifteen patients were studied: Seven had one 1.5T and one 3T scan and eight had two 3T EEG-fMRI studies. Equal numbers of events of the same interictal epileptic discharge (IED) were included, and IED-related blood oxygenation level dependent (BOLD) results were compared.

Key findings

In 1.5T-3T comparisons, five patients had BOLD responses in both studies, but in fou

SUBMITTER: Gholipour T 

PROVIDER: S-EPMC3792085 | biostudies-literature | 2011 Mar

REPOSITORIES: biostudies-literature