Trends and properties of human cerebral cortex: correlations with cortical myelin content.

ABSTRACT: "In vivo Brodmann mapping" or non-invasive cortical parcellation using MRI, especially by measuring cortical myelination, has recently become a popular research topic, though myeloarchitectonic cortical parcellation in humans previously languished in favor of cytoarchitecture. We review recent in vivo myelin mapping studies and discuss some of the different methods for estimating myelin content. We discuss some ways in which myelin maps may improve surface registration and be useful for cross-modal and cross-species comparisons, including some preliminary cross-species results. Next, we consider neurobiological aspects of why some parts of cortex are more myelinated than others. Myelin content is inversely correlated with intracortical circuit complexity - in general, more myelin content m

SUBMITTER: Glasser MF 

PROVIDER: S-EPMC3795824 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature