Identification of novel predictor classifiers for inflammatory bowel disease by gene expression profiling.

ABSTRACT:

Background

Improvement of patient quality of life is the ultimate goal of biomedical research, particularly when dealing with complex, chronic and debilitating conditions such as inflammatory bowel disease (IBD). This is largely dependent on receiving an accurate and rapid diagnose, an effective treatment and in the prediction and prevention of side effects and complications. The low sensitivity and specificity of current markers burden their general use in the clinical practice. New biomarkers with accurate predictive ability are needed to achieve a personalized approach that take the inter-individual differences into consideration.

Methods

We performed a high throughput approach using microarray gene expression profiling of colon pinch biopsies from IBD patients to identif

SUBMITTER: Montero-Melendez T 

PROVIDER: S-EPMC3796518 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature