Use of expert panels to define the reference standard in diagnostic research: a systematic review of published methods and reporting.

ABSTRACT:

Background

In diagnostic studies, a single and error-free test that can be used as the reference (gold) standard often does not exist. One solution is the use of panel diagnosis, i.e., a group of experts who assess the results from multiple tests to reach a final diagnosis in each patient. Although panel diagnosis, also known as consensus or expert diagnosis, is frequently used as the reference standard, guidance on preferred methodology is lacking. The aim of this study is to provide an overview of methods used in panel diagnoses and to provide initial guidance on the use and reporting of panel diagnosis as reference standard.

Methods and findings

PubMed was systematically searched for diagnostic studies applying a panel diagnosis as reference standard published up to May 3

SUBMITTER: Bertens LC 

PROVIDER: S-EPMC3797139 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature