Effect of including cancer mortality on the cost-effectiveness of aspirin for primary prevention in men.

ABSTRACT:

Background

Recent data suggest that aspirin may be effective for reducing cancer mortality.

Objective

To examine whether including a cancer mortality-reducing effect influences which men would benefit from aspirin for primary prevention.

Design

We modified our existing Markov model that examines the effects of aspirin among middle-aged men with no previous history of cardiovascular disease or diabetes. For our base case scenario of 45-year-old men, we examined costs and life-years for men taking aspirin for 10 years compared with men who were not taking aspirin over those 10 years; after 10 years, we equalized treatment and followed the cohort until death. We compared our results depending on whether or not we included a 22 % relative reduction in cancer mortality, ba

SUBMITTER: Pignone M 

PROVIDER: S-EPMC3797356 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature