Dopamine controls the neural dynamics of memory signals and retrieval accuracy.

ABSTRACT: The human brain is capable of differentiating between new and already stored information rapidly to allow optimal behavior and decision-making. Although the neural mechanisms of novelty discrimination were often described as temporally constant (ie, with specific latencies), recent electrophysiological studies have demonstrated that the onset of neural novelty signals (ie, differences in event-related responses to new and old items) can be accelerated by reward motivation. While the precise physiological mechanisms underlying this acceleration remain unclear, the involvement of the neurotransmitter dopamine in both novelty and reward processing suggests that enhanced dopamine levels in the context of reward prospect may have a role. To investigate this hypothesis, we used magnetoencephalog

SUBMITTER: Apitz T 

PROVIDER: S-EPMC3799060 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature