Enantioselective catalytic transannular ketone-ene reactions.

ABSTRACT: Highly enantio- and diastereoselective transannular ketone-ene reactions are catalyzed by a new chromium(III) triflate tridentate Schiff base complex. Electronically unactivated keto-olefins undergo heteroene reactions at ambient temperature to afford enantioenriched bicyclic alcohols, common structural motifs in natural products. The kinetic resolution of a configurationally stable planar-chiral cyclodecenone is also described.

SUBMITTER: Rajapaksa NS 

PROVIDER: S-EPMC3799808 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature