Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials.

ABSTRACT:

Objective

Little is known about the participation of racial/ethnic minorities, women, and the elderly into critical care clinical trials. We sought to characterize the representation of racial and ethnic minorities, women, and older patients in clinical trials of patients with acute lung injury and to determine the reasons for nonenrollment.

Design, setting, and patients

We performed a cross-sectional analysis of pooled screening logs from 44 academic hospitals participating in three multicentered, randomized, controlled trials conducted by the Acute Respiratory Distress Syndrome Network from 1996 to 2005.

Interventions

None.

Measurements and main results

We calculated odds ratios of enrollment for age, sex, racial groups, and the odds ratio for the presence of

SUBMITTER: Cooke CR 

PROVIDER: S-EPMC3799957 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature