Utilization of epidermal growth factor receptor (EGFR) testing in the United States: a case study of T3 translational research.

ABSTRACT:

Purpose

We examined hospital use of the epidermal growth factor receptor assay in patients with lung cancer in the United States. Our goal was to inform the development of a model to predict phase 3 translation of guideline-directed molecular diagnostic tests.

Methods

This was a retrospective observational study. Using logistic regression, we analyzed the association between hospitals' institutional and regional characteristics and the likelihood that an epidermal growth factor receptor assay would be ordered.

Results

Significant institutional predictors included affiliation with an academic medical center (odds ratio, 1.48; 95% confidence interval, 1.20-1.83), participation in a National Cancer Institute clinical research cooperative group (odds ratio, 2.06, 1.66-2.5

SUBMITTER: Lynch JA 

PROVIDER: S-EPMC3800006 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature