Whole-genome sequencing of two North American Drosophila melanogaster populations reveals genetic differentiation and positive selection.

ABSTRACT: The prevailing demographic model for Drosophila melanogaster suggests that the colonization of North America occurred very recently from a subset of European flies that rapidly expanded across the continent. This model implies a sudden population growth and range expansion consistent with very low or no population subdivision. As flies adapt to new environments, local adaptation events may be expected. To describe demographic and selective events during North American colonization, we have generated a data set of 35 individual whole-genome sequences from inbred lines of D. melanogaster from a west coast US population (Winters, California, USA) and compared them with a public genome data set from Raleigh (Raleigh, North Carolina, USA). We analysed nuclear and mitochondrial genomes and descr

SUBMITTER: Campo D 

PROVIDER: S-EPMC3800041 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature